• Curcumin-In-Deformable Liposomes-In-ChitosanHydrogel as a Novel Wound Dressing 

      Ternullo, Selenia; Schulte Werning, Laura; Holsæter, Ann Mari; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-20)
      A liposomes-in-hydrogel system as an advanced wound dressing for dermal delivery of curcumin was proposed for improved chronic wound therapy. Curcumin, a multitargeting poorly soluble active substance with known beneficial properties for improved wound healing, was incorporated in deformable liposomes to overcome its poor solubility. Chitosan hydrogel served as a vehicle providing superior wound ...
    • Electrospinning of chloramphenicol-containing nanofibrous dressings for treatment of chronic wounds 

      Schulte Werning, Laura; Murugaiah, Anjanah; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Conference object; Konferansebidrag, 2021-03-10)
      <p><i>Background</i> An efficient treatment is crucial to overcome the delayed healing process and high infection rate in chronic wounds. Nanofibrous dressings, having a nano‐sized fiber structure, can enhance cell ingrowth and support the healing process. In addition, nanofibers can deliver active ingredients e.g. antibiotics into the wound to treat wound infection. By incorporating broad‐spectrum ...
    • Multifunctional Nanofibrous Dressing with Antimicrobial and Anti-Inflammatory Properties Prepared by Needle-Free Electrospinning 

      Schulte Werning, Laura; Murugaiah, Anjanah; Singh, Bhupender; Johannessen, Mona; Engstad, Rolf Einar; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-21)
      An active wound dressing should address the main goals in wound treatment, which are improved wound healing and reduced infection rates. We developed novel multifunctional nanofibrous wound dressings with three active ingredients: chloramphenicol (CAM), beta-glucan (βG) and chitosan (CHI), of which βG and CHI are active nanofiber-forming biopolymers isolated from the cell walls of Saccharomyces ...